Indian Perspective on AYUSH System of Medicines
AYUSH Systems of Medicine, a Viable Solution for COVID-19 amidst the Uncertainty of Vaccination & Herd Immunity – an Indian Perspective Hima Bindu Ponnam1* and Butchi Raju Akondi Homoeopathic Clinical Research Unit, Central Council for Research in Homoeopathy, Under Ministry of AYUSH, Government of India, Hyderabad, Telangana, India; drdewdrop@gmail.com Department of Clinical Pharmacy and Pharmacology, Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia; drraju2020@gmail.com In this era of major modern medical advancements, a way of lurking uncertainty still persists about human life in combating the upcoming novel viral diseases as present SARS-CoV2 virus causing COVID-19. COVID-19 tremendously pushed the whole world into a wave of anxiety and stress in terms of uncertainty about life and death. As on 17th May 2020, in India, the infected cases are 90,927 amongst which active cases 53,946, deaths are 2872, and cured discharged cases are 34,1081. The Case fatality rate as on this date is around 3.2% in India and the recovery rate is 37.5% which seems to be very positive when compared with other suffering countries of the world. A precise introspection in this regard is very much essential at this juncture of endangered human life. Before analyzing the fact, lets us see why such an immense uncertainty prevailing regarding the treatment of COVID-19 and its containment. The last 2-3 months of fact sheet enabled us to understand that 81% of cases of COVID-19 were asymptomatic, 14% severely exhibited with symptoms and only 5% needed critical care. At this stage where no known established treatment regimen is prevailing, the management of COVID-19 remains a challenge to the whole world. The treatment approach presently being utilized world-wide is the allopathic system of medicine with different opinions from experts including retroviral medicines combination used in HIV cases & remsedivir developed for Ebola), Hydroxy-chloroquine (HCQ). These broad-spectrum antibiotic regimens being used currently are meant for treating bacterial infections coming after a virus attack but not to treat COVID-19 directly and they pose a lot many adverse side effects as on record. In critical cases, oxygen therapy, intravenous fluid infusion, and life-saving ventilator therapy are being utilized in combination as per the condition of the patient. Leaving aside the treatment options, let us evaluate the other possible strategies for the containment of the virus. The most awaited and the discussed option is the Vaccination which is under different phases of trials in different countries at present. Vaccination is the administration of a vaccine to help the immune system develop protection from a disease and it contains a microorganism or virus in a weakened, live or killed state, or protein or toxins from the organism. When we go through the history of vaccinations, it is evident that preparing a vaccine for an epidemic is a lengthy and expensive process, which may take about a year or two or even more. Also how far the vaccination would succeed is doubtful on account of different strains of the virus and also a study by Li and her collaborators recently found it evident that the SARS-CoV2 virus has acquired mutations capable of substantially changing its pathogenicity and also its mutations again throwing us into uncertainty. Coming to the Herd Immunity (HI), a much-out spoken concept by many expert epidemiologists. Herd Immunity happens when so many people in a community become immune to an infectious disease that it stops the disease from spreading. It happens in two ways: one is that many people contract the disease and in time build up an immune response to it (natural immunity) and the other many people are vaccinated against the disease to achieve immunity. As we already discussed the option of vaccination which have a higher chance of failure. Coming to the natural herd immunity, in which we are leaving the population at risk to contract the disease. Again this depends on the average number known as the basic reproductive number commonly symbolically designated as “R0” – that is the average number of other persons that an infectious person will infect with an agent in a completely susceptible population. This may become very risky when the clinical consequences of the infection are greater for the vulnerable low immunity groups (children, old age, and pregnant women). The United Kingdom initially opted for it but in view of the fatal consequences of increasing mortality rates had to withdraw opting for lockdown restrictions in their country. Ultimately, herd immunity option also exhibits a risk of mortality and uncertainty. Finally comes the much-weighted statement about COVID-19 prevention is possessing a natural strong immunity within the human body. Moving into the introspection of the Indian perspective, India is a country full of rich ancient culture and heritage lasting from thousands of years. Many ancient scriptures envisaged the use of a vast number of natural remedies in boosting the immunity of a person. In India when we critically observe the treatment regimens opted for, it has been found that a considerable amount of people give preference to Ayurveda, Yoga, Unani, Siddha, Sow Rigpa, and Homoeopathy (AYUSH) systems of medicine which are the rich heritage of India. Even the Indian Government supports these systems of medicine under the National Health Mission and taken necessary steps to mainstream these systems of medicine to bring an equal status to the allopathic system of medicine. The Indian government has formed a separate Ministry of AYUSH in 2014 to strengthen the potential of these systems of medicine in reaching the masses. The Confederation of Indian Industry website states that the AYUSH is currently a $10 billion market and is expected to grow to a $15 billion market by 2020 (https://www.ciiblog.in/industry/ayush-is-booming-in-india/). According to AYUSH systems, the common reasons for preferring these treatment options includes lesser side effects, effective disease management, and improvement of quality of life and health promotion, higher preventive potential, and cost-effectiveness. All these systems are highly known for their holistic approach of treatment and their main modus operandi of remedies is to strengthen the natural immunity of the individual which in turn stimulates the human body to fight with