PSM News

Dec 13,2024 Washington: Some early breast cancer patients can safely avoid specific surgeries, according to two studies exploring ways to lessen treatment burdens. One new study, published in the New England Journal of Medicine, examines whether removing lymph nodes is always necessary in early breast cancer. Another in the Journal of the American Medical Association suggests a new approach to a type of breast cancer called ductal carcinoma in situ, or DCIS. The research was discussed Thursday at the San Antonio Breast Cancer Symposium. DCIS and active monitoring Every year, about 50,000 women in the US are diagnosed with ductal carcinoma in situ, or DCIS, where the cells that line milk ducts become cancerous, but the nearby breast tissue remains healthy. Many choose to have surgery, although it’s unclear whether they could instead take a “wait-and-see” approach with more frequent monitoring. The new study, based on two years of data, suggests that such active monitoring is a safe alternative to surgery for many of these women, though some doctors will want to see if the results hold up over time. “This is an option that patients should consider for their DCIS,” said Dr Virginia Kaklamani of the University of Texas Health Science Center San Antonio, who was not involved in the research. “For a long time, we’ve had the feeling that we’re overtreating some patients with DCIS. This is a confirmation of what we suspected is happening.” Taking a more cautious view, Dr Monica Morrow of Memorial Sloan Kettering Cancer Center, who was not involved in the study, said a two-year study isn’t long enough to draw conclusions. The finding is based on following more than 950 U.S. patients randomly assigned to surgery or active monitoring. All had low-risk DCIS with no sign of invasive cancer. They had the type of DCIS that responds to hormone-blocking drugs and many in the study took those drugs as part of their treatment. After two years, the rates of invasive cancer were low and did not differ significantly between the groups, with about 6% in the surgery group and about 4% in the monitoring group diagnosed with invasive cancer. Among patients in the monitoring group, changes spotted on a mammogram would prompt a biopsy. They also could opt for surgery at any time for any reason. Some study participants didn’t stick with the treatment they were randomly assigned. So in a separate analysis looking at those who actually had surgery or not, the rates of invasive cancer were about 9% for the surgery group and 3% for the monitoring group. Tina Clark, 63, of Buxton, Maine, joined the study after being diagnosed with DCIS in 2019. Randomly assigned to the monitoring-only group, she was able to avoid surgery and radiation during a time when she was raising a teenage nephew and going through the illness and death of her husband. “I feel just so grateful and fortunate that I found this study when I did,” Clark said. She has mammograms every six months to keep watch on the DCIS in her right breast, which has not advanced. The mammograms spotted a small cancer in her other breast in 2023, unrelated to the DCIS. She had a lumpectomy to remove it. “If you’re diagnosed with low-risk DCIS, you have time to understand more about your disease and understand what your options are,” said study author Dr Shelley Hwang of Duke University School of Medicine. Lymph nodes and early breast cancer Women having surgery for breast cancer often also have what’s called a sentinel lymph node biopsy where a few lymph nodes in the armpit are removed to check for spreading cancer. But removing lymph nodes can cause lasting pain and arm swelling, so research is underway to determine when it can be avoided. A study in Europe last year showed that older women with small tumours could safely avoid the added surgery. In the new study, researchers in Germany looked at whether women with early breast cancer who were planning to have breast-conserving surgery could safely skip having lymph nodes removed. They followed 4,858 women who were randomly assigned to have lymph nodes removed or not. After five years, about 92% of women in both groups were still alive and free of cancer. “Removing lymph nodes does not improve survival, and the risk of cancer coming back in the armpit is quite low when lymph nodes are not removed,” said Morrow, who added that some women will still need the lymph node procedure to help determine which treatment drugs they should take after surgery. Source: Healthworld

Dec 14,2024 New Delhi: The Supreme Court on Friday sought responses from the Centre and others on a plea seeking directions to make available anti-venom and snakebite treatment at health centres, hospitals and medical colleges to save lives of victims. A bench of Justices B R Gavai and K V Viswanathan agreed to hear the petition and issued notices to the Centre, states and union territories seeking their responses. “Issue notice, returnable in four weeks,” the bench said. The plea filed by Shailendra Mani Tripathi, an advocate, said the country faced a significant public health crisis due to the scarcity of anti-venom which was crucial for treating snakebites. “India has the highest rate of snakebite deaths globally, with approximately 58,000 fatalities each year. Despite this much of high mortality rate there is scarcity of anti-venom (polyvenom),” the plea, filed through advocate Chand Qureshi, said. It said many rural areas in the country lacked adequate stocks of anti-venom, leading to delays in treatment for snakebite victims. The plea has sought directions to conduct snakebite prevention health mission and snakebite public awareness campaigns to reduce mortality, especially in rural India. It also sought directions to establish snakebite treatment and care units along with special trained doctors as per standard medical norms in government district hospitals and government medical colleges. Source: Healthworld

Dec 13,2024 Dehradun: The 10th World Ayurveda Congress and AROGYA Expo began here on Thursday with Prime Minister Narendra Modi asserting that the ancient Indian system of medicine has the potential to strengthen the global healthcare systems . In a message read out at the inaugural function of the event, Modi also reiterated the government’s commitment to promote Ayurveda. Ayurveda has the potential to strengthen the global healthcare systems as it focuses on providing “comprehensive remedies” to various health problems and lays equal emphasis on prevention, nutrition and mental health, the prime minister said. Modi expressed confidence that the four-day meet will expedite the promotion of Ayurveda at the global level and asked the delegates to come out with a new “blueprint” for the purpose. The event is being attended by over 5,500 delegates, including about 350 overseas delegates from 54 countries. Addressing the event, Uttarakhand Chief Minister Pushkar Singh Dhami said the state government is working towards implementing the country’s “first” yoga policy. It will play an important role in bringing about a new revolution in the field of health by bringing Ayurveda and yoga together on a big scale, he said. Dhami described Uttarakhand as the land of Ayurveda and AYUSH since ancient times because of its herbal wealth. Uttarakhand is the first Himalayan state where the event is being held. Dhami thanked Prime Minister Modi for the event being organised in Dehradun. He said the presence of representatives from more than 50 countries and nearly 6,000 experts in the program and more than 250 stalls set up in the expo are giving evidence of the global acceptance of Ayurveda. He expressed hope that the conference will create new opportunities for cooperation and business along with mutual knowledge sharing and promotion of various research works in the field of Ayurveda. The state government has requested the Union Ministry of AYUSH to establish an All India Institute of Ayurveda in the state, which will prove to be a milestone in the field of Ayurveda education and research, Dhami said. He also spoke about steps being taken by the state government to continuously promote Ayurveda. Dhami said 300 AYUSH-based ‘Ayushman Arogya Kendras’ are being operated in the state, while AYUSH consultation is being given by more than 70 experts through the e-Sanjeevani portal. He further said that 50-bed AYUSH hospitals are being set up in each district, while one village in each district is being established as a model AYUSH village to promote the production of Ayurvedic herbs. The chief minister said the state government has implemented the ‘Ayush Policy’ to accelerate the production of AYUSH manufacturing, wellness, education, research and medicinal plants. Along with this, the state government will start AYUSH tele-consultation in the coming years and set up 50 new yoga and wellness centres. The chief minister requested the experts to promote the English names of herbs along with their Hindi names, which will facilitate the access of local herbs to the global market. Union Minister of State for AYUSH (Independent Charge) Prataprao Jadhav said the initiatives taken in the field of AYUSH during the last 10 years have led to an eight-fold increase in the production of AYUSH products. Now, AYUSH and herbal products are being exported to more than 150 countries of the world, he said. The Union minister said that Ayurveda is also now moving forward by adopting the technology of Artificial Intelligence and Machine Learning tools. Jadhav said the central government is trying to establish AYUSH medicine centres at district, tehsil and village level to make all the medicines of Ayurveda available under one roof. The first such centre has been started in All India Institute of Ayurveda, Delhi. He said that with the opening of such centres across the country, AYUSH doctors will be able to easily prescribe Ayurvedic medicines to patients. He said that the World Ayurveda Congress will prove to be a confluence of new ideas, ancient culture and innovations. Source: Healthworld

Dec 13,2024 New Delhi: The incidence rate of tuberculosis (TB) in India has shown a 17.7 per cent decline from 237 per 1,00,000 population in 2015 to 195 per 1,00,000 population in 2023, Union Health Minister J P Nadda told Lok Sabha on Friday. The TB deaths has reduced by 21.4 per cent from 28 per lakh population in 2015 to 22 per lakh population in 2023, he said while responding to a question. Shorter oral regimen for drug resistant TB was introduced in 2021. This intervention has improved treatment success rates of drug resistant TB patients from 68 per cent in 2020 to 75 per cent in 2022, he said. The government of India has implemented a National Strategic Plan (2017-2025) with a view to eliminating TB by 2025, five years ahead of the United Nation’s Sustainable Development Goal (SDG) target of 2030. The ministry implements the National Tuberculosis Elimination Programme (NTEP) under the aegis of the National Health Mission (NHM). “The NTEP has made significant efforts to make India TB free. The incidence rate of TB in India has shown a 17.7 per cent decline from 237 per 100,000 population in 2015 to 195 per 100,000 population in 2023. TB deaths has reduced by 21.4 per cent from 28 per lakh population in 2015 to 22 per lakh population in 2023,” the minister said. The steps taken by the government in all states and Union Territories (UTs) to achieve the mentioned goals include targeted interventions in high TB burden areas through state and district specific strategic plans, provision of free drugs and diagnostics to TB patients and active TB case-finding through campaigns in key vulnerable and co-morbid populations. The government has also initiated integration of Ayushman Arogya Mandir with TB screening and treatment services, private sector engagement with incentives for notification and management of TB cases, scaling up of molecular diagnostic laboratories to sub-district levels and expansion of coverage under Ni-kshay Poshan Yojana for nutritional support to TB patients, Nadda stated. The initiatives also include intensified Information, Education and Communication (IEC) interventions to reduce stigma, enhance community awareness and improve health seeking behaviour, convergence of efforts and resources of line ministries for TB elimination, provision of TB preventive treatment to contacts of TB patients and vulnerable population, tracking of notified TB cases through Ni-kshay portal and providing additional nutritional, diagnostic and vocational support to TB patients and household contacts under Ni-kshay Mitra initiative, the minister said. Source: Healthworld

Dec 13,2024 Geneva: After making a temporary effort to support their public healthcare spending during the peak pandemic phase, the World Health Organisation has reported that the governments across the world have cut down their average per capita spending on health in 2022 from 2021. Released on the Universal Healthcare Coverage Day, the 2024 Global Heath Expenditure Report by the World Health Organization (WHO) states, “that the average per capita government spending on health in all country income groups fell in 2022 from 2021 after a surge in the early pandemic years.” It also alarms that, “government spending on health is crucial to delivering UHC (Universal Healthcare Coverage) and its deprioritisation can have dire consequences in a context where 4.5 billion people worldwide lack access to basic health services and 2 billion people face financial hardship due to health costs. Speaking over the development Dr Tedros Adhanom Ghebreyesus, WHO Director-General, said, “while access to health services has been improving globally, using those services is driving more and more people into financial hardship or poverty. Universal Health Coverage Day is a reminder that health for all means everyone can access the health services they need, without financial hardship.” As per the global healthcare advocacy body, during the COVID-19 pandemic in 2020–2022, public spending on health – mainly via government health budgets –enabled health systems to respond quickly to the emergency. Government funding ensured that more people were protected and more lives were saved, in particular population-based public health interventions, versus other health financing schemes, during times of health emergencies. “Public funding needs to budget for an affordable package of essential health services – from health promotion to prevention, treatment, rehabilitation and palliative care – using a primary health care approach”, the report added. WHO’s report also flags that, “protecting people from the financial burden caused by out-of-pocket expenditure is fundamental but on the contrary out-of-pocket spending remained the main source of health financing in 30 low- and lower-middle-income countries.” In 20 of these countries, more than half of total health spending in the country was paid for by patients out of their pocket, which contributes to the cycle of poverty and vulnerability. The World Health Organisation has been tracking the healthcare expenditure of countries for the last 25 years and has established a Global Health Expenditure Database which consists of health expenditure data of more than 190 countries since 2000–and the Global Health Expenditure Report, which has been published annually since 2017. Source: Healthworld

Nov 22, 2024 New Delhi: The Commission for Air Quality Management (CAQM) comprehensively reviewed sector-specific enforcement actions taken by the concerned NCR State governments/Government of National Capital Territory of Delhi (GNCTD) and Punjab to abate air pollution in the region. During the 18th meeting of the Sub-Committee on Safeguarding and Enforcement held on Wednesday ordered to ensure strict enforcement of measures to control air pollution in the National Capital Region (NCR) According to the press release of CAQM, after a detailed review of action taken by NCR State Governments/ GNCTD, the following directions were given by the Commission in which “(a) mismatch in a number of cases where EC has imposed and the cases where FIR has been filed u/s 223 of BNS, 2023 needs to be sorted out for Punjab and Haryana.” “Gap in cumulative amount of EC imposed and EC realised needs to analysed and redressed on an urgent basis. Inspection protocol for verification of fire incidences be revised to within 24 hrs from 48 hours, especially by Punjab,” Meanwhile, for all Delhi NCR states all actions prescribed under different stages of GRAP need to be enforced strictly in true letter and spirit. “Special attention must be given to all identified hotspots in Delhi. The same must be taken up on priority, except those actions which are prohibited under GRAP. Special attention must be given for controlling the C&D dust and all C&D activities must stop keeping in provisions under GRAP Inspections must be intensified in the entire Delhi NCR. Stringent actions must be taken against the violators as per directions issued by the Commission,” it added. For all Delhi NCR States, a special drive must be launched for impounding of EOL vehicles. “The data from Traffic Police, Transport agencies and municipal authorities must be compiled and submitted to the Commission through the nodal agency. Efforts for challaning the non-possession of PUC must be enhanced.” The auditing of the PUC Centres needs to be carried out on priority in all Delhi NCR states. “The entry points of Delhi must be checked for the non-permitted vehicles and proper arrangements be made at the border. The congestion points and barricades on the road to be managed properly. Barricading to be done only during inspection and to be removed immediately thereafter. Patrolling vehicles to check for these points creating congestion and inform the Traffic Police to take immediate corrective action,” it added. The Commission also directed to augment the MRSMs on priority to achieve the target for GNCTD and Haryana. “Expedite the collection of pending Environmental Compensation (ECs) from violators. Ensure compliance to the directions of the Hon’ble Supreme Court regarding brick kilns regulation for NCR districts of Haryana, UP and Rajasthan,” it added. Moreover, for all Delhi NCR states the biomass and MSW burning activities must be stopped in open areas through strict enforcement of regulations and improved waste management practices. “Pending complaints from citizens on different Apps and social media platforms till date must be resolved in a time-bound manner. CAQM must be tagged on social media page while forwarding and resolving the complaint so that they are properly tracked and monitored,” it added. The Nodal officers for all agencies have been directed to coordinate actions in their respective agencies and concerned DPCC to also monitor the actions by different agencies, besides action required to be taken by themselves. “Daily reporting of actions under GRAP must be provided to the Commission on daily basis without fail Officials of concerned agencies shall be held accountable for any laxity in the enforcement of the directions of the Commission and the same may attract action under provisions of CAQM Act for all Delhi NCR states,” it said. The authorities of Punjab and Haryana were asked to ensure the implementation of in-situ and ex-situ measures for the prevention of paddy stubble burning. Further, it was reiterated that considering the prevailing AQI levels in Delhi-NCR, there should not be any laxity in monitoring and taking enforcement actions after expeditious verification of fire incidences within 24 hrs. It was committed at the meeting by all implementing agencies that they will regularly review air pollution control measures and take strict and effective action across various sectors as well as those listed under GRAP. A layer of smog has engulfed several parts of Delhi, but the quality of the air improved marginally. After the air quality in the national capital reeled into ‘severe’ and ‘severe plus’ category for the past few days, the level of air pollution slightly improved on Thursday as the air quality fell into to ‘very poor’ category with a thin layer of smog reducing visibility in several parts of Delhi. Source: Economic Times

Nov 20, 2024 Bhopal: Madhya Pradesh Chief Minister Mohan Yadav has said that the state government has been very serious about the medical education and services, adding that Medicity will be built in Ujjain district. The proposed Medicity in Ujjain will include a medical college along with comprehensive facilities such as nursing, paramedical services, research centres, and accommodations for doctors, specialists, and staff. “The Madhya Pradesh government has been serious about medical education and medical services. Under the leadership of Prime Minister Narendra Modi, a different concept has come to the country in medical services, through the AWSH department. I would like to say that in the last 20 years, the Madhya Pradesh government has taken revolutionary steps in the medical sector,” CM Yadav told ANI. He highlighted that currently there are 17 medical colleges at government level in the state and eight more colleges will be constructed soon in the state. “There were 5 medical colleges here in 2004-05. Now in 2024, there are 17 medical colleges operational at the government level. Eight more colleges are in the pipeline which will be built here. I would like to mention that Ujjain Medical College will have the new concept of Medicity, given by PM Modi. It will not be just a medical college but nursing, paramedical, different types of research labs and staff quarters, doctor quarters, administrative building, new research campus will be there. The Madhya Pradesh government will try to provide all the facilities required in the Medicity,” CM Yadav added. The Chief Minister also extended greetings to the people of the state and Ujjain district and shared that he would perform the Bhoomi Pujan of the campus. He further added that during the ‘Simhastha’ period, there would be a crowd of about 15 crores in Ujjain. Even in normal times, about 5 to 7 crore travellers are visiting Ujjain every year. Therefore, the formation of Medicity here is useful and important. Notably, Simhastha Kumbh is held every 12 years in the Ujjain city. The last ‘Simhastha’ took place in 2016 and the next would be held in 2028. (ANI) Source: Economic Times

Nov 18, 2024 New Delhi: Delhi Chief Minister Atishi on Monday said north India is facing a medical emergency due to hazardous air quality caused by stubble burning. Addressing a press conference here, Atishi said the BJP-led central government has been doing politics over the issue of pollution but has taken no step to check stubble burning in states like Haryana, Rajasthan, Uttar Pradesh and Madhya Pradesh all ruled by the saffron party. Lauding the AAP-ruled Punjab, she said it is the only state where the cases of stubble burning have come down significantly. In BJP-ruled states, they have gone up, she claimed. Atishi said due to Delhi’s worsening air quality, the elderly are being hospitalised and children need inhalers and steroids to breathe. Delhi’s air quality worsened to the ‘severe plus’ category on Monday with the city recording an AQI of 484. Tighter pollution control measures, including a ban on truck entry and suspension of construction at public projects, came into force in the morning. The dense toxic smog caused visibility to drop sharply in the morning. Source: Economic Times

Nov 20, 2024 The Centre for Chronic Disease Control (CCDC), a non-profit organisation working in the healthcare sector, on Tuesday (November 19, 2024), announced the completion of a study on drug treatment optimisation for blood pressure in India. The research initiative tested the effectiveness of three double anti-hypertensive pill combinations in South Asian populations with uncontrolled hypertension. Conducted over two years in collaboration with the All India Institute of Medical Sciences (AIIMS) and Imperial College, London, the study demonstrated that all the three combinations were equally effective and safe in regulating blood pressure. The study evaluated three two-drug combinations — Amlodipine + Perindopril, Amlodipine + Indapamide, and Perindopril + Indapamide — and revealed that all three combinations were similarly effective in achieving blood pressure (BP) control. South Asians account for 25% of the global population, and India alone is burdened with over 300 million individuals suffering from high BP. This is the first randomised study to test the choice of anti-hypertensives in them. “These findings will provide clinicians a roadmap for addressing the burden of hypertension,” said a press release. Dorairaj Prabhakaran, executive director, CCDC, and one of the principal investigators said that the study demonstrates that a once-a-day single pill combination of two blood pressure lowering drugs can control blood pressure effectively. “This is in conformity with several international guidelines, eases the management of hypertension, and provides wider choices to doctors. With this evidence, healthcare professionals can be better equipped in recommending any of these three combination therapies in managing hypertension among South Asians,” he said. For the study, the participant base spanned 35 clinical sites across all four regions of India and incorporated both rural and urban populations. The participants, aged 30 to 79 years, had a wide range of clinical profiles, making the results applicable to a diverse population. “The study bridges a critical knowledge gap in hypertension treatment for South Asians. It provides novel evidence to choose any of these three combinations to treat high blood pressure in Indians. It is important to note that the blood pressure control achieved with a single pill a day in 70% of the participants in the study exceeded the current control rates in India by five times. This has important implications for management of hypertension, a major public health burden in India,” Ambuj Roy, Professor, Department of Cardiology, AIIMS, said. Source: The Hindu

Nov 23, 2024 HYDERABAD: In a big boost to state’s pharma sector, six companies have come forward to establish green pharma units and expand their operations in the Green Pharma City. The firms MSN Group, Laurus Labs, Gland Pharma, Dr Reddy’s Laboratories, Aurobindo Pharma and Hetero Labs signed MoUs with the state government in the presence of Chief Minister A Revanth Reddy on Friday. These companies will invest around Rs 5,620 crore and create 12,490 jobs. The government has agreed to allot land to these companies in the Green Pharma City. As per the MoUs, the MSN Group will establish a manufacturing unit and an R&D centre and Aurobindo Pharma and Laurus Labs will set up formulation units, while Gland Pharma will build an R&D centre as well as injectable drug substance manufacturing units. Dr Reddy’s Laboratories will set up an injectable and biosimilars unit, while Hetero Labs will establish a finishing dose and injectable drugs manufacturing unit. The chief minister directed officials to expedite the land allotment process and provide necessary facilities to ensure that construction works begin within the next four months. TGIIC chairperson Nirmala Jagga Reddy, Special Chief Secretary to Industries Department Jayesh Ranjan and representatives of the six companies were present on the occasion. Source: Indian Express